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13/05/2015
The Scientific Impact Paper (SIP) looked at the reasons for barriers when it came to obstetrics drugs, explaining that maternal and perinatal disease accounts for around 7% of global disease.
However, less than 5% of the number of drugs being developed to combat cardiovascular disease have been designed to help new mothers or pregnant women, it added.
It has called for more to be done to help mothers and babies.
The SIP did address the fact that challenges are in place, such as expensive development costs, ethical and regulatory issues and difficulties in trial design; but it also set out a number of strategies that could improve the development of new obstetric treatments.
They include finding drugs to treat obstetric conditions that are already licensed for treatment of disease outside of pregnancy. As the safety profile of such drugs is already known, this could shorten the time to clinical use, the report found. It also suggested the establishment of a database of the use of drugs used during pregnancy to monitor their safety, effectiveness, and long-term outcomes on child development. In addition, preference should be given to the use of licensed drugs for an obstetric condition, when available, to encourage pharmaceutical companies to spend time and money investigating and licensing drugs in pregnancy.
Carmel Lloyd, head of education at the Royal College of Midwives (RCM), said: "It is important that women taking medication to treat medical conditions, such as epilepsy, discuss this with their GP or medical physician prior to becoming pregnant."
Dr Sadaf Ghaem-Maghami, Chair of the RCOG's scientific advisory committee, added: "The strategies outlined by the RCOG are designed to encourage pharmaceutical companies to invest in drugs to treat pregnant and new mothers, while sharing information will make drug choices easier for both doctors and their patients."
(JP)
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Obstetric Drugs Are Focus Of RCOG Report
A new paper by the Royal College of Obstetricians and Gynaecologists (RCOG) has addressed how more drugs can be developed for use in obstetrics. It added that the development was "overdue".The Scientific Impact Paper (SIP) looked at the reasons for barriers when it came to obstetrics drugs, explaining that maternal and perinatal disease accounts for around 7% of global disease.
However, less than 5% of the number of drugs being developed to combat cardiovascular disease have been designed to help new mothers or pregnant women, it added.
It has called for more to be done to help mothers and babies.
The SIP did address the fact that challenges are in place, such as expensive development costs, ethical and regulatory issues and difficulties in trial design; but it also set out a number of strategies that could improve the development of new obstetric treatments.
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They include finding drugs to treat obstetric conditions that are already licensed for treatment of disease outside of pregnancy. As the safety profile of such drugs is already known, this could shorten the time to clinical use, the report found. It also suggested the establishment of a database of the use of drugs used during pregnancy to monitor their safety, effectiveness, and long-term outcomes on child development. In addition, preference should be given to the use of licensed drugs for an obstetric condition, when available, to encourage pharmaceutical companies to spend time and money investigating and licensing drugs in pregnancy.
Carmel Lloyd, head of education at the Royal College of Midwives (RCM), said: "It is important that women taking medication to treat medical conditions, such as epilepsy, discuss this with their GP or medical physician prior to becoming pregnant."
Dr Sadaf Ghaem-Maghami, Chair of the RCOG's scientific advisory committee, added: "The strategies outlined by the RCOG are designed to encourage pharmaceutical companies to invest in drugs to treat pregnant and new mothers, while sharing information will make drug choices easier for both doctors and their patients."
(JP)
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