UK Wedding News
06/12/2013
The study, which has been published in the journal PLOS ONE, is said to be the first of its kind to look at the failure rates for each stage of IVF for different age groups.
The duration of fertility problems prior to IVF treatment is also associated with poor outcomes at the various stages of treatment, but its impact is not as great.
For the research, experts looked at data from 121,744 women across the UK who underwent their first cycle of IVF between 2000 and 2007 using their own eggs. They found that the chances of a woman having a baby following IVF go "very rapidly downhill" from the age of 37.
Even after a pregnancy has been confirmed, women aged 38-39 were 43% more likely to have a miscarriage than women aged 18-34, while women aged 40-42 were almost twice as likely to lose the baby as women aged 18-34.
Professor Siladitya Bhattacharya, Professor of Reproductive Medicine at the University of Aberdeen, who led the research, said: "IVF comprises a number of key steps, each of which has to be successfully achieved before the next stage can be attempted. We found that age impacted on every single hurdle that has to be overcome during the emotional rollercoaster that is IVF.
"This influence of age is sustained at each stage of the IVF process. There is no point during an IVF treatment - even in women who have done well in a preceding stage - when age ceases to matter.
"Age has the capacity to increase the risk of treatment failure even in women who respond to hormonal treatment, have eggs harvested and embryos replaced."
Professor Bhattacharya concluded: "Many couples want to understand how their chances of having a baby evolve over the course of an IVF treatment. Previous work has been able to offer a global prediction of success in IVF.
"We hope our study provides a more accurate and dynamic way of predicting a couple's chances of treatment failure as they negotiate each step of IVF."
(JP)
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Women's Age Does Affect IVF Success
A new study by the University of Aberdeen has revealed that a woman's age affects the outcome of each step of IVF treatment.The study, which has been published in the journal PLOS ONE, is said to be the first of its kind to look at the failure rates for each stage of IVF for different age groups.
The duration of fertility problems prior to IVF treatment is also associated with poor outcomes at the various stages of treatment, but its impact is not as great.
For the research, experts looked at data from 121,744 women across the UK who underwent their first cycle of IVF between 2000 and 2007 using their own eggs. They found that the chances of a woman having a baby following IVF go "very rapidly downhill" from the age of 37.
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Even after a pregnancy has been confirmed, women aged 38-39 were 43% more likely to have a miscarriage than women aged 18-34, while women aged 40-42 were almost twice as likely to lose the baby as women aged 18-34.
Professor Siladitya Bhattacharya, Professor of Reproductive Medicine at the University of Aberdeen, who led the research, said: "IVF comprises a number of key steps, each of which has to be successfully achieved before the next stage can be attempted. We found that age impacted on every single hurdle that has to be overcome during the emotional rollercoaster that is IVF.
"This influence of age is sustained at each stage of the IVF process. There is no point during an IVF treatment - even in women who have done well in a preceding stage - when age ceases to matter.
"Age has the capacity to increase the risk of treatment failure even in women who respond to hormonal treatment, have eggs harvested and embryos replaced."
Professor Bhattacharya concluded: "Many couples want to understand how their chances of having a baby evolve over the course of an IVF treatment. Previous work has been able to offer a global prediction of success in IVF.
"We hope our study provides a more accurate and dynamic way of predicting a couple's chances of treatment failure as they negotiate each step of IVF."
(JP)
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